CCT Gamma antibody
Goat anti Human CCT gamma antibody recognizes chaperonin containing TCP1 complex (CCT) gamma, also known as TCP-1-gamma or hTRiC5.
CCT gamma, encoded by CCT3 gene, is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for CCT3. In addition, a pseudogene of CCT3 has been found on chromosome 8 (provided by RefSeq, Aug 2010).
Goat anti Human CCT gamma antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
CCT gamma, encoded by CCT3 gene, is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for CCT3. In addition, a pseudogene of CCT3 has been found on chromosome 8 (provided by RefSeq, Aug 2010).
Goat anti Human CCT gamma antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti CCT gamma detects a band of approximately 60 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3) 0.5 % BSA
- Immunogen
- Peptide with the sequence C-CHKKKGDDQSRQGG, from the C Terminus of the protein sequence.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P49368
- Entrez Gene
- CCT3
- GO Terms
- GO:0051082 unfolded protein binding
- GO:0005886 plasma membrane
- GO:0005524 ATP binding
- GO:0005856 cytoskeleton
- GO:0051084 'de novo' posttranslational protein folding
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of CCT Gamma antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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