Caveolin 1 (pTyr14) antibody
In response to oxidative stress, caveolin-1 is phosphorylated by Src tyrosine kinase family members, Src, Abl or Fyn at tyrosine 14.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to caveolin 1 (pTyr14) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding tyrosine 14 of human caveolin 1
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q03135
- Entrez Gene
- CAV1
- GO Terms
- GO:0000139 Golgi membrane
- GO:0000188 inactivation of MAPK activity
- GO:0005515 protein binding
- GO:0001570 vasculogenesis
- GO:0001666 response to hypoxia
- GO:0001937 negative regulation of endothelial cell proliferation
- GO:0007596 blood coagulation
- GO:0005102 receptor binding
- GO:0005783 endoplasmic reticulum
- GO:0005811 lipid particle
- GO:0005901 caveola
- GO:0006641 triglyceride metabolic process
- GO:0006816 calcium ion transport
- GO:0006940 regulation of smooth muscle contraction
- GO:0007519 skeletal muscle tissue development
- GO:0009267 cellular response to starvation
- GO:0010524 positive regulation of calcium ion transport into cytosol
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0015485 cholesterol binding
- GO:0016050 vesicle organization
- GO:0016323 basolateral plasma membrane
- GO:0016324 apical plasma membrane
- GO:0016504 peptidase activator activity
- GO:0019217 regulation of fatty acid metabolic process
- GO:0019915 lipid storage
- GO:0030193 regulation of blood coagulation
- GO:0030514 negative regulation of BMP signaling pathway
- GO:0030857 negative regulation of epithelial cell differentiation
- GO:0031295 T cell costimulation
- GO:0031623 receptor internalization
- GO:0032091 negative regulation of protein binding
- GO:0032507 maintenance of protein location in cell
- GO:0032570 response to progesterone stimulus
- GO:0032947 protein complex scaffold
- GO:0033137 negative regulation of peptidyl-serine phosphorylation
- GO:0033138 positive regulation of peptidyl-serine phosphorylation
- GO:0033484 nitric oxide homeostasis
- GO:0042632 cholesterol homeostasis
- GO:0051260 protein homooligomerization
- GO:0043409 negative regulation of MAPKKK cascade
- GO:0043627 response to estrogen stimulus
- GO:0044419 interspecies interaction between organisms
- GO:0045019 negative regulation of nitric oxide biosynthetic process
- GO:0045907 positive regulation of vasoconstriction
- GO:0046209 nitric oxide metabolic process
- GO:0048471 perinuclear region of cytoplasm
- GO:0048554 positive regulation of metalloenzyme activity
- GO:0050900 leukocyte migration
- GO:0050998 nitric-oxide synthase binding
- GO:0050999 regulation of nitric-oxide synthase activity
- GO:0051480 cytosolic calcium ion homeostasis
- GO:0051592 response to calcium ion
- GO:0051899 membrane depolarization
- GO:0060056 mammary gland involution
- GO:0070836 caveola assembly
- GO:0090090 negative regulation of canonical Wnt receptor signaling pathway
- GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
- Regulatory
- For research purposes only
Applications of Caveolin 1 (pTyr14) antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | 1/500 | 1/2000 |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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|
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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|
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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|
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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|
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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|
Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
Further Reading
-
Williams, T.M. & Lisanti, M.P. (2005) Caveolin-1 in oncogenic transformation, cancer, and metastasis
Am J Physiol Cell Physiol. 288 (3): C494-506.
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