Catenin Gamma antibody

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Anti Catenin Gamma Antibody gallery image 1 — Western blot analysis of cell and tissue lysates using Rabbit anti catenin gamma antibody

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Rabbit anti Catenin Gamma

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: Catenin Gamma

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AHP2447 Datasheet Datasheet SDS SDS	WB	50 µl		Log in	Get Quote
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Rabbit anti catenin gamma antibody recognizes catenin gamma, also known as junction plakoglobin (JUP), or desmoplakin-3. Catenin gamma is a junctional plaque protein and a member of the catenin protein family. It is present in desmosomes and intermediate junctions, playing an important role in cytoskeleton arrangement and function.

Target Species: Human
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat Expected from Sequence; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Antiserum Preparation: Antiserum to catenin gamma was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.02% Sodium Azide
50% Glycerol
Immunogen: Recombinant human catenin gamma
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Target Species	Cross Reactivity
Mouse
Rat	Expected from Sequence

Store at -20^oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/500	1/2000

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Western Blotting: Rabbit anti catenin gamma antibody detects a band of approximately 90 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt: P14923
Entrez Gene: JUP
GO Terms: GO:0000902 cell morphogenesis; GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway; GO:0003181 atrioventricular valve morphogenesis; GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development; GO:0003704 specific RNA polymerase II transcription factor activity; GO:0003713 transcription coactivator activity; GO:0005102 receptor binding; GO:0005199 structural constituent of cell wall; GO:0005634 nucleus; View More GO Terms; GO:0005915 zonula adherens; GO:0005916 fascia adherens; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0007369 gastrulation; GO:0007398 ectoderm development; GO:0007399 nervous system development; GO:0009898 internal side of plasma membrane; GO:0015629 actin cytoskeleton; GO:0016323 basolateral plasma membrane; GO:0016331 morphogenesis of embryonic epithelium; GO:0016342 catenin complex; GO:0016477 cell migration; GO:0019901 protein kinase binding; GO:0019903 protein phosphatase binding; GO:0030018 Z disc; GO:0030057 desmosome; GO:0032993 protein-DNA complex; GO:0034332 adherens junction organization; GO:0034747 Axin-APC-beta-catenin-GSK3B complex; GO:0042153 RPTP-like protein binding; GO:0042307 positive regulation of protein import into nucleus; GO:0042803 protein homodimerization activity; GO:0043588 skin development; GO:0045294 alpha-catenin binding; GO:0045296 cadherin binding; GO:0048599 oocyte development; GO:0050982 detection of mechanical stimulus; GO:0051091 positive regulation of transcription factor activity; GO:0071603 endothelial cell-cell adhesion; GO:0071665 gamma-catenin-TCF7L2 complex; GO:0071681 cellular response to indole-3-methanol; GO:0090263 positive regulation of canonical Wnt receptor signaling pathway