Rabbit anti catenin gamma antibody recognizes catenin gamma, also known as junction plakoglobin (JUP), or desmoplakin-3. Catenin gamma is a junctional plaque protein and a member of the catenin protein family. It is present in desmosomes and intermediate junctions, playing an important role in cytoskeleton arrangement and function.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to catenin gamma was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human catenin gamma
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
negative regulation of heart induction by canonical Wnt receptor signaling pathway
atrioventricular valve morphogenesis
negative regulation of Wnt receptor signaling pathway involved in heart development
specific RNA polymerase II transcription factor activity
transcription coactivator activity
structural constituent of cell wall
cytoskeletal anchoring at plasma membrane
nervous system development
internal side of plasma membrane
basolateral plasma membrane
morphogenesis of embryonic epithelium
protein kinase binding
protein phosphatase binding
adherens junction organization
RPTP-like protein binding
positive regulation of protein import into nucleus
protein homodimerization activity
detection of mechanical stimulus
positive regulation of transcription factor activity
endothelial cell-cell adhesion
cellular response to indole-3-methanol
positive regulation of canonical Wnt receptor signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Catenin Gamma antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti catenin gamma antibody detects a band of approximately 90 kDa in cell lysates and tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available