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Catenin Gamma antibody

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Western blot analysis of cell and tissue lysates using Rabbit anti catenin gamma antibody

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Rabbit anti Catenin Gamma

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Catenin Gamma

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Technical Suppport
Product Code Applications Pack Size List Price Your Price Qty
AHP2447
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader
Search for Batch Specific Datasheets

Rabbit anti catenin gamma antibody recognizes catenin gamma, also known as junction plakoglobin (JUP), or desmoplakin-3. Catenin gamma is a junctional plaque protein and a member of the catenin protein family. It is present in desmosomes and intermediate junctions, playing an important role in cytoskeleton arrangement and function.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to catenin gamma was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human catenin gamma
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti catenin gamma antibody detects a band of approximately 90 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt
P14923
Entrez Gene
JUP
GO Terms
GO:0000902 cell morphogenesis
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway
GO:0003181 atrioventricular valve morphogenesis
GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development
GO:0003704 specific RNA polymerase II transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005102 receptor binding
GO:0005199 structural constituent of cell wall
GO:0005634 nucleus
GO:0005915 zonula adherens
GO:0005916 fascia adherens
GO:0007016 cytoskeletal anchoring at plasma membrane
GO:0007369 gastrulation
GO:0007398 ectoderm development
GO:0007399 nervous system development
GO:0009898 internal side of plasma membrane
GO:0015629 actin cytoskeleton
GO:0016323 basolateral plasma membrane
GO:0016331 morphogenesis of embryonic epithelium
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030018 Z disc
GO:0030057 desmosome
GO:0032993 protein-DNA complex
GO:0034332 adherens junction organization
GO:0034747 Axin-APC-beta-catenin-GSK3B complex
GO:0042153 RPTP-like protein binding
GO:0042307 positive regulation of protein import into nucleus
GO:0042803 protein homodimerization activity
GO:0043588 skin development
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
GO:0048599 oocyte development
GO:0050982 detection of mechanical stimulus
GO:0051091 positive regulation of transcription factor activity
GO:0071603 endothelial cell-cell adhesion
GO:0071665 gamma-catenin-TCF7L2 complex
GO:0071681 cellular response to indole-3-methanol
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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