Catenin Gamma antibody
Rabbit anti catenin gamma antibody recognizes catenin gamma, also known as junction plakoglobin (JUP), or desmoplakin-3. Catenin gamma is a junctional plaque protein and a member of the catenin protein family. It is present in desmosomes and intermediate junctions, playing an important role in cytoskeleton arrangement and function.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to catenin gamma was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant human catenin gamma
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P14923
- Entrez Gene
- JUP
- GO Terms
- GO:0000902 cell morphogenesis
- GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway
- GO:0003181 atrioventricular valve morphogenesis
- GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development
- GO:0003704 specific RNA polymerase II transcription factor activity
- GO:0003713 transcription coactivator activity
- GO:0005102 receptor binding
- GO:0005199 structural constituent of cell wall
- GO:0005634 nucleus
- GO:0005915 zonula adherens
- GO:0005916 fascia adherens
- GO:0007016 cytoskeletal anchoring at plasma membrane
- GO:0007369 gastrulation
- GO:0007398 ectoderm development
- GO:0007399 nervous system development
- GO:0009898 internal side of plasma membrane
- GO:0015629 actin cytoskeleton
- GO:0016323 basolateral plasma membrane
- GO:0016331 morphogenesis of embryonic epithelium
- GO:0016342 catenin complex
- GO:0016477 cell migration
- GO:0019901 protein kinase binding
- GO:0019903 protein phosphatase binding
- GO:0030018 Z disc
- GO:0030057 desmosome
- GO:0032993 protein-DNA complex
- GO:0034332 adherens junction organization
- GO:0034747 Axin-APC-beta-catenin-GSK3B complex
- GO:0042153 RPTP-like protein binding
- GO:0042307 positive regulation of protein import into nucleus
- GO:0042803 protein homodimerization activity
- GO:0043588 skin development
- GO:0045294 alpha-catenin binding
- GO:0045296 cadherin binding
- GO:0048599 oocyte development
- GO:0050982 detection of mechanical stimulus
- GO:0051091 positive regulation of transcription factor activity
- GO:0071603 endothelial cell-cell adhesion
- GO:0071665 gamma-catenin-TCF7L2 complex
- GO:0071681 cellular response to indole-3-methanol
- GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
- Regulatory
- For research purposes only
Applications of Catenin Gamma antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti catenin gamma antibody detects a band of approximately 90 kDa in cell lysates and tissue lysates under reducing conditions
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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|
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
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