Casein Kinase 1 Delta antibody

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Goat anti Human Casein Kinase 1 Delta (C-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP796 E P* WB 0.1 ml
Goat anti Human casein kinase 1 delta antibody recognizes human casein kinase 1 delta, also known as protein kinase CK1 delta or Tau-protein kinase CSNK1D.

Casein kinase 1 delta is a 415 amino acid ~47 kDa member of the casein kinase 1 family of protein kinases common to all eukaryotic cells, although tissue distribution and subcellular localization may vary between isoforms. Casein kinase 1 delta has been implicated in the regulation of p53 (Venerando et al. 2010). Upregulation of casein kinase 1 delta expression has been reported in Alzheimer's disease hippocampus and its association with tau-containing bodies suggests that it may play a role in the abnormal phosphorylation of tau (Li et al. 2005).

Product Details

Target Species
Human
Product Form
Serum - liquid
Antiserum Preparation
Antisera to human casein kinase 1 delta were raised by repeated immunisations of goats with highly purified antigen.
Preservative Stabilisers
0.1%Sodium Azide
Immunogen
Synthetic peptide corresponding to amino acids 310-327 of human casein kinase 1 delta

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P48730 Related reagents
Entrez Gene
CSNK1D Related reagents
GO Terms
GO:0000086 G2/M transition of mitotic cell cycle
GO:0005515 protein binding
GO:0001934 positive regulation of protein phosphorylation
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0016055 Wnt receptor signaling pathway
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032922 circadian regulation of gene expression
GO:0042752 regulation of circadian rhythm
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
Regulatory
For research purposes only

Applications of Casein Kinase 1 Delta antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Immunohistology - Paraffin 1 1/200
Western Blotting
  1. 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB

Product Specific References

References for Casein Kinase 1 Delta antibody

  1. Babiker, A.A. et al. (2006) Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin.
    Prostate. 66 (7): 675-86.