Carboxypeptidase H antibody
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Rabbit anti Human carboxypeptidase H antibody recognises carboxypeptidase H also known as carboxypeptidase E, enkephalin convertase, CPH and CPE.
Carboxypeptidase H functions to remove residual C-terminal arginine or lysine residues remaining after initial endoprotease cleavage during prohormone processing. Carboxypeptidase H may be found in secretory granules of the pancreatic islets, adrenal gland and pituitary gland.
Carboxypeptidase H functions to remove residual C-terminal arginine or lysine residues remaining after initial endoprotease cleavage during prohormone processing. Carboxypeptidase H may be found in secretory granules of the pancreatic islets, adrenal gland and pituitary gland.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse Bovine Monkey - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Serum - liquid
- Antiserum Preparation
- Antisera to carboxypeptidase H were raised by repeated immunisations of rabbits with highly purified antigen.
- Preservative Stabilisers
0.1% Sodium Azide - Immunogen
- Synthetic peptide derived from the C-terminus of carboxypeptidase H, conjugated to KLH.
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P16870
- Entrez Gene
- CPE
- GO Terms
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0003214 cardiac left ventricle morphogenesis
- GO:0004181 metallocarboxypeptidase activity
- GO:0005576 extracellular region
- GO:0006464 protein modification process
- GO:0007218 neuropeptide signaling pathway
- GO:0008270 zinc ion binding
- Regulatory
- For research purposes only
Applications of Carboxypeptidase H antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Frozen | 1/100 | 1/200 | |
| Immunoprecipitation | |||
| Western Blotting | 1/500 | 1/1000 |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Adrenal gland
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Useful Reagents Available
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|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
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