Carboxypeptidase H antibody

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Rabbit anti Human Carboxypeptidase H (Mature N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP672 C* IP* WB 0.1 ml
Rabbit anti Human carboxypeptidase H antibody recognizes carboxypeptidase H, also known as carboxypeptidase E, entephalin convertase, CPH and CPE.

This enzyme functions to remove residual C-terminal arginine or lysine residues remaining after initial endoprotease cleavage during prohormone processing. Carboxypeptidase H may be found in secretory granules of the pancreatic islets, adrenal gland and pituitary gland.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
Bovine
Monkey
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Serum - liquid
Antiserum Preparation
Antisera to carboxypeptidase H were raised by repeated immunisations of rabbits with highly purified antigen.
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
Synthetic peptide derived from N-terminus of carboxypeptidase H.

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P16870 Related reagents
Entrez Gene
CPE Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0003214 cardiac left ventricle morphogenesis
GO:0004181 metallocarboxypeptidase activity
GO:0005576 extracellular region
GO:0006464 protein modification process
GO:0007218 neuropeptide signaling pathway
GO:0008270 zinc ion binding
Regulatory
For research purposes only

Applications of Carboxypeptidase H antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Frozen 1
Immunoprecipitation 2
Western Blotting 1/500 1/1000
  1. 1 Fixation with methanol is recommended.
  2. 2 Sample pre-treatment with 0.1% w/v SDS and 1% v/v TritonX 100 is required.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Immunohistology
*Bio-Rad recommend methanol fixation for this purpose.
Histology Positive Control Tissue
Adrenal gland

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
TidyBlot™ Western Blot Detection Reagent:HRP STAR209P 0.5 ml WB*