BMP-7 antibody

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Rabbit anti BMP-7

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00829 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human BMP-7 antibody recognizes the bone morphogenetic protein 7, also known as osteogenic protein 1 (OP-1).

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by BMP7 has a proposed role in early development and possible bone inductive activity (provided by RefSeq, Jul 2008).

Rabbit anti Human BMP-7 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species: Human
Western Blotting: Anti BMP-7 antibody recognizes a band of approximately 49 kDa in HeLa cell lysates
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide
2% Sucrose
Immunogen: Synthetic peptide corresponding to a portion of BMP-7

Storage Information

Storage: Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee: 12 months from date of despatch

More Information

UniProt: P18075
Entrez Gene: BMP7
GO Terms: GO:0001503 ossification; GO:0001657 ureteric bud development; GO:0001823 mesonephros development; GO:0001837 epithelial to mesenchymal transition; GO:0005125 cytokine activity; GO:0005615 extracellular space; GO:0040007 growth; GO:0008083 growth factor activity; GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0030501 positive regulation of bone mineralization; GO:0030509 BMP signaling pathway; GO:0032582 negative regulation of gene-specific transcription; GO:0034504 protein localization to nucleus; GO:0042326 negative regulation of phosphorylation; GO:0043401 steroid hormone mediated signaling pathway; GO:0043407 negative regulation of MAP kinase activity; GO:0045669 positive regulation of osteoblast differentiation; GO:0045839 negative regulation of mitosis; GO:0051216 cartilage development; GO:0060389 pathway-restricted SMAD protein phosphorylation; GO:0060395 SMAD protein signal transduction; GO:0072125 negative regulation of glomerular mesangial cell proliferation
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory: For research purposes only

Applications of BMP-7 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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