BMP-4 antibody

ISO 9001 Quality Assurance Manufacturing | Print

Anti BMP-4 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with BMP-4 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 8 second exposure. Arrow points to BMP-4 (molecular weight 47 kDa)

Filter by Application:

Rabbit anti BMP-4

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: BMP-4

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VPA00302 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
	Log in

Rabbit anti Human BMP-4 antibody recognizes bone morphogenetic protein 4 (BMP-4) also known as bone morphogenetic protein 2B (BMP-2B).

BMP-4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo at an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of the BMP-4 gene sequence has been described and three variants reported, all encoding an identical protein (provided by RefSeq, Jul 2008).

Rabbit anti Human BMP-4 antibody detects a band of 47 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti BMP-4 detects a band of approximately 47 kDa in A549 cell lysate.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
2% Sucrose
Immunogen: Synthetic peptide corresponding to the C-terminal region of human BMP-4
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P12644
Entrez Gene: BMP4
GO Terms: GO:0000186 activation of MAPKK activity; GO:0001649 osteoblast differentiation; GO:0001658 branching involved in ureteric bud morphogenesis; GO:0001823 mesonephros development; GO:0001938 positive regulation of endothelial cell proliferation; GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis; GO:0002320 lymphoid progenitor cell differentiation; GO:0003197 endocardial cushion development; GO:0003279 cardiac septum development; View More GO Terms; GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis; GO:0005125 cytokine activity; GO:0005578 proteinaceous extracellular matrix; GO:0005615 extracellular space; GO:0008083 growth factor activity; GO:0009791 post-embryonic development; GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter; GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter; GO:0010595 positive regulation of endothelial cell migration; GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0016563 transcription activator activity; GO:0016564 transcription repressor activity; GO:0030501 positive regulation of bone mineralization; GO:0032967 positive regulation of collagen biosynthetic process; GO:0033088 negative regulation of immature T cell proliferation in thymus; GO:0034504 protein localization to nucleus; GO:0042056 chemoattractant activity; GO:0042326 negative regulation of phosphorylation; GO:0043065 positive regulation of apoptosis; GO:0043401 steroid hormone mediated signaling pathway; GO:0043407 negative regulation of MAP kinase activity; GO:0045662 negative regulation of myoblast differentiation; GO:0045669 positive regulation of osteoblast differentiation; GO:0045839 negative regulation of mitosis; GO:0045843 negative regulation of striated muscle tissue development; GO:0048286 lung alveolus development; GO:0048392 intermediate mesodermal cell differentiation; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0051216 cartilage development; GO:0060391 positive regulation of SMAD protein import into nucleus; GO:0060395 SMAD protein signal transduction; GO:0060433 bronchus development; GO:0060502 epithelial cell proliferation involved in lung morphogenesis; GO:0060503 bud dilation involved in lung branching; GO:0061036 positive regulation of cartilage development; GO:0061155 pulmonary artery endothelial tube morphogenesis; GO:0070244 negative regulation of thymocyte apoptosis; GO:0070700 BMP receptor binding; GO:0071893 BMP signaling pathway involved in nephric duct formation; GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway; GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway; GO:0072125 negative regulation of glomerular mesangial cell proliferation; GO:0090184 positive regulation of kidney development; GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis; GO:0090194 negative regulation of glomerulus development; GO:2000005 negative regulation of metanephric S-shaped body morphogenesis; GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis