BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis.
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to human BIM (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
- Synthetic peptide sequence C-FNAYYARRLEK from the C-Terminal region of BIM (NP_619528; NP_996886; NP_619529).
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
Applications of BIM antibody
|Application Name||Verified||Min Dilution||Max Dilution|
- Western Blotting
- AHP2074 detects a band of approximately 23kDa in K562 cell lysates.