Beta 2 Microglobulin antibody

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Sheep anti Human Beta 2 Microglobulin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
6240-0134 C E 0.25 ml
Sheep anti Human beta 2 microglobulin antibody recognizes native beta 2 microglobulin, a component of MHC class I molecules, present on all nucleated cells. Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients (Sasaki et al. 1997). Also known as B2M, this protein can be used as a prognostic marker for HIV infection (Fahey et al. 1990).

Sheep anti Human beta 2 microglobulin antibodyt shows minimal reactivity with related serum and urinary proteins.
Sheep anti Human beta 2 microglobulin antibody has not been cross-absorbed, so may react with beta 2 microglobulin from other species.

Product Details

Target Species
Human
Product Form
Serum - liquid
Antiserum Preparation
Antisera to human beta 2 microglobulin were raised by repeated immunisation of sheep with highly purified antigen. Whole serum is supplied.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Purified beta 2 microglobulin from human urine.

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P61769 Related reagents
Entrez Gene
B2M Related reagents
GO Terms
GO:0000139 Golgi membrane
GO:0005515 protein binding
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0042612 MHC class I protein complex
GO:0006955 immune response
GO:0016032 viral reproduction
GO:0031901 early endosome membrane
GO:0050690 regulation of defense response to virus by virus
GO:0060333 interferon-gamma-mediated signaling pathway
Regulatory
For research purposes only

Applications of Beta 2 Microglobulin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/1000 1/4000
Immunohistology - Frozen 1/25 1/400
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Sheep IgG (H/L):Biotin 5184-2304 1.5 ml C E F WB
Donkey anti Sheep/Goat IgG:DyLight®488 STAR88D488GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:DyLight®549 STAR88D549GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:DyLight®649 STAR88D649GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:FITC STAR88F 1 mg C
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB