BETA-1 Adrenergic Receptor antibody
Rabbit anti BETA-1 Adrenergic Receptor
Beta-1 adrenergic receptor antibody recognizes the beta-1 adrenergic receptor, also known as RHR, ADRB1, or BETA1AR .
- Product Type
- PrecisionAb™ Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
| Product Code | Applications | Datasheet | MSDS | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|---|
| VPA00859 | WB | 100 µl |
Rabbit anti Human beta-1 adrenergic receptor antibody recognizes the beta-1 adrenergic receptor, also known as RHR, ADRB1 and BETA1AR .
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure (provided by RefSeq, Jul 2008).
Rabbit anti Human beta-1 adrenergic receptor antibody detects bands of 50-55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure (provided by RefSeq, Jul 2008).
Rabbit anti Human beta-1 adrenergic receptor antibody detects bands of 50-55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti beta-1 adrenergic receptor antibody recognizes a band of approximately 50-55 kDa in HEK293 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide corresponding to the C-terminal region of human beta-1 adrenergic receptor
- Instructions For Use
- Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- As supplied, 12 months from date of despatch
More Information
- UniProt
- P08588 Related reagents
- Entrez Gene
- ADRB1 Related reagents
- GO Terms
- GO:0004940 beta1-adrenergic receptor activity
- GO:0005887 integral to plasma membrane
- GO:0030819 positive regulation of cAMP biosynthetic process
- GO:0031694 alpha-2A adrenergic receptor binding
- GO:0046982 protein heterodimerization activity
- Acknowledgements
- PrecisionAb™ is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of BETA-1 Adrenergic Receptor antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
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Secondary Antibodies Available
| Description | Product Code | Pack Size | Applications | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | 2 ml | WB |
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