BETA-1 Adrenergic Receptor antibody
Rabbit anti Human beta-1 adrenergic receptor antibody recognizes the beta-1 adrenergic receptor, also known as RHR, ADRB1 and BETA1AR .
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure (provided by RefSeq, Jul 2008).
Rabbit anti Human beta-1 adrenergic receptor antibody detects bands of 50-55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure (provided by RefSeq, Jul 2008).
Rabbit anti Human beta-1 adrenergic receptor antibody detects bands of 50-55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti beta-1 adrenergic receptor antibody recognizes a band of approximately 50-55 kDa in HEK293 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide corresponding to the C-terminal region of human beta-1 adrenergic receptor
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08588
- Entrez Gene
- ADRB1
- GO Terms
- GO:0004940 beta1-adrenergic receptor activity
- GO:0005887 integral to plasma membrane
- GO:0030819 positive regulation of cAMP biosynthetic process
- GO:0031694 alpha-2A adrenergic receptor binding
- GO:0046982 protein heterodimerization activity
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of BETA-1 Adrenergic Receptor antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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