BETA-1 Adrenergic Receptor antibody

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Rabbit anti BETA-1 Adrenergic Receptor

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00859
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human beta-1 adrenergic receptor antibody recognizes the beta-1 adrenergic receptor, also known as RHR, ADRB1 and BETA1AR .

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure (provided by RefSeq, Jul 2008).

Rabbit anti Human beta-1 adrenergic receptor antibody detects bands of 50-55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti beta-1 adrenergic receptor antibody recognizes a band of approximately 50-55 kDa in HEK293 cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on Protein A
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide corresponding to the C-terminal region of human beta-1 adrenergic receptor

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P08588
Entrez Gene
ADRB1
GO Terms
GO:0004940 beta1-adrenergic receptor activity
GO:0005887 integral to plasma membrane
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0031694 alpha-2A adrenergic receptor binding
GO:0046982 protein heterodimerization activity
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of BETA-1 Adrenergic Receptor antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml