Bcl-6 antibody
Rabbit anti Bcl-6 antibody recognizes Bcl-6 (B-cell lymphoma 6 protein). The Bcl-6 transcription factor, as the name implies, has clinical relevance as mutation may result in B cell lymphoma.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal - Immunogen
- Synthetic peptide mapping to amino acid residues near the C-terminus of human Bcl-6
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P41182
- Entrez Gene
- BCL6
- GO Terms
- GO:0000060 protein import into nucleus, translocation
- GO:0000122 negative regulation of transcription from RNA polymerase II promoter
- GO:0005515 protein binding
- GO:0002634 regulation of germinal center formation
- GO:0002903 negative regulation of B cell apoptosis
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005634 nucleus
- GO:0006974 response to DNA damage stimulus
- GO:0008270 zinc ion binding
- GO:0016564 transcription repressor activity
- GO:0030308 negative regulation of cell growth
- GO:0043065 positive regulation of apoptosis
- GO:0043565 sequence-specific DNA binding
- GO:0045749 negative regulation of S phase of mitotic cell cycle
- Regulatory
- For research purposes only
Applications of Bcl-6 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin | 20 | 40 ug/ml | |
| Immunoprecipitation | 10 | 20 ug/ml | |
| Western Blotting | 0.5 | 4.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti Bcl-6 antibody recognizes a band of approximately 95 kDa in Jurkat cell lysates
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
|
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
|
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
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