BAP31 is a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in the BAP31 gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of BAP31 results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. (provided by RefSeq, Jan 2012).
Goat anti Human BAP31 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti BAP31 detects a band of approximately 28 kDa in MCF7 cell lysates.
- Product Form
- Purified IgG - liquid
- Goat polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3) 0.5 % BSA
- Peptide with the sequence C-QAAVDGPMDKKEE, from the C Terminus of the protein sequence.
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0016192 vesicle-mediated transport
- GO:0005102 receptor binding
- GO:0005829 cytosol
- GO:0005887 integral to plasma membrane
- GO:0005789 endoplasmic reticulum membrane
- GO:0006886 intracellular protein transport
- GO:0006921 cellular component disassembly involved in apoptosis
- GO:0006955 immune response
- GO:0033116 ER-Golgi intermediate compartment membrane
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of BAP31 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Donkey anti Sheep/Goat IgG:HRP||STAR88P||C E P WB||1 ml|