BAP31 antibody

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WB ResetRabbit anti BAP31
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- BAP31
Rabbit anti Human BAP31 antibody recognizes the human chaperone protein, B-cell receptor-associated protein 31, also known as BAP31. BAP31 is a 246 amino acid ~28 kDa conserved multi pass type III integral transmembrane protein of the endoplasmic reticulum, containing two caspase cleavage sites within its cytosolic domain. BAP31 appears to be a multi-functional ER-associated transport protein, identified through its association with membrane IgD in B-cells (Adachi et al. 1996). Several proteins associate with BAP31, including the Beta2 integrin receptor CD11b/CD18 (Zen et al. 2004), non-muscle gamma-actin and myosin B heavy chain (Ducret et al. 2003). BAP31 associates with Bcl-2 and cleavage by initiator caspases including caspase 1 and 8 generating a membrane-integrated p20 fragment which is itself a potent inducer of apoptosis when expressed ectopically (Breckenridge et al. 2003). Rabbit anti Human BAP31 antibody detects BAP31 as a band of approximately 24 kDa in a wide range of human cell line lysates. |
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- Target Species
- Human
- Western Blotting
- Rabbit anti BAP31 detects a band of approximately 24 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- 17 amino acid peptide located near human BAP31 C-terminus.
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1000 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (H/L):HRP |
- Synonyms
- p28
- UniProt
- P51572
- Entrez Gene
- BCAP31
- GO Terms
- GO:0016192 vesicle-mediated transport
- GO:0005102 receptor binding
- GO:0005829 cytosol
- GO:0005887 integral to plasma membrane
- GO:0005789 endoplasmic reticulum membrane
- GO:0006886 intracellular protein transport
- GO:0006921 cellular component disassembly involved in apoptosis
- GO:0006955 immune response
- GO:0033116 ER-Golgi intermediate compartment membrane
- View More GO Terms
VPA00088

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