Rabbit anti BAK (N-Terminal) antibody recognizes BAK also known as Bcl-2-like protein 7, apoptosis regulator BAK and Bcl-2 homologous antagonist/killer. As the name implies Bcl-2 homologous antagonist plays a role in mediating apoptosis via counteracting anti-apoptotic Bcl-2 activity.
- Target Species
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide mapping the N-terminus of human BAK
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 12 months from date of despatch
- Entrez Gene
- GO Terms
release of cytochrome c from mitochondria
metal ion binding
mitochondrial outer membrane
induction of apoptosis by intracellular signals
activation of pro-apoptotic gene products
identical protein binding
establishment or maintenance of transmembrane electrochemical gradient
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
regulation of mitochondrial membrane permeability
protein heterodimerization activity
regulation of mitochondrial membrane potential
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of BAK antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti Human BAK (N-Terminal) antibody recognizes a band of approximately 30 kDa in Jurkat cell lysate
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Secondary Antibodies Available