BAG3 antibody

Goat anti BAG3

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
BAG3

Product Code Applications Pack Size List Price Your Price Qty
VPA00114
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl
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Search for Batch Specific Datasheets

Goat anti Human BAG3 antibody recognizes the BAG family molecular chaperone regulator 3 (BAG3), also known as Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis and docking protein CAIR-1.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. BAG3 contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (provided by RefSeq, Jul 2008).

Goat anti Human BAG3 antibody detects a band of 85 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti BAG3 detects a band of approximately 85 kDa in MCF7 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution
TRIS buffered saline.
Preservative Stabilisers
0.02% Sodium Azide (NaN3) 0.5 % BSA
Immunogen
Peptide with the sequence C-SSMTDTPGNPAAP, from the C terminus of the protein sequence.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P C E P WB 1 ml loader
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loader
Description Donkey anti Sheep/Goat IgG:HRP

UniProt
O95817
Entrez Gene
BAG3
GO Terms
GO:0006457 protein folding
GO:0006915 apoptosis
GO:0005829 cytosol
GO:0006916 anti-apoptosis
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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