Rabbit anti ARNT2 antibody recognizes human aryl hydrocarbon receptor nuclear translocator 2 (encoded by ARNT2), also known as class E basic helix-loop-helix protein 1 or bHLHe1. ARNT2 is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. By forming complexes with other members of the bHLH PAS family (such as single minded homologue 1), ARNT2 plays a significant role in CNS development.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to ARNT2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human ARNT2
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
response to hypoxia
in utero embryonic development
sequence-specific DNA binding transcription factor activity
signal transducer activity
central nervous system development
aryl hydrocarbon receptor binding
transcription regulator activity
protein heterodimerization activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of ARNT2 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti ARNT2 antibody detects both ARNT2 isoforms at approximately 77 kDa and 79 kDa in tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available
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