ARNT2 antibody

Rabbit anti ARNT2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
ARNT2

Product Code Applications Pack Size List Price Your Price Qty
AHP2437
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SDS Safety Datasheet SDS
P WB 50 µl loader
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Rabbit anti ARNT2 antibody recognizes human aryl hydrocarbon receptor nuclear translocator 2 (encoded by ARNT2), also known as class E basic helix-loop-helix protein 1 or bHLHe1. ARNT2 is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. By forming complexes with other members of the bHLH PAS family (such as single minded homologue 1), ARNT2 plays a significant role in CNS development.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to ARNT2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human ARNT2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti ARNT2 antibody detects both ARNT2 isoforms at approximately 77 kDa and 79 kDa in tissue lysates under reducing conditions

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UniProt
Q9HBZ2
Entrez Gene
ARNT2
GO Terms
GO:0001666 response to hypoxia
GO:0001701 in utero embryonic development
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0007417 central nervous system development
GO:0017162 aryl hydrocarbon receptor binding
GO:0030528 transcription regulator activity
GO:0046982 protein heterodimerization activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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