ARNT antibody
Filter by Application:
WB ResetRabbit anti ARNT
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- ARNT
Antibody Quality and 
Unrivaled 
| Rabbit anti ARNT antibody recognizes aryl hydrocarbon receptor nuclear translocator (encoded by the gene ARNT), also known as hypoxia-inducible factor 1-beta (HIF1-beta) or bHLHe2. ARNT is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. ARNT forms complexes with either hypoxia-inducible factor 1-alpha (HIF-1 alpha) or aryl hydrocarbon receptor (AhR), ARNT is involved in the adaptive response to stress caused by dioxins and hypoxia. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to ARNT was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant human ARNT
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti ARNT antibody detects a band of approximately 87 kDa in cell lysates under reducing conditions. Rabbit anti ARNT antibody also appears to detect a modified form of ARNT at a higher molecular weight.
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
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| Description | TidyBlot Western Blot Detection Reagent:HRP | ||||||
- UniProt
- P27540
- Entrez Gene
- ARNT
- GO Terms
- GO:0001666 response to hypoxia
- GO:0001938 positive regulation of endothelial cell proliferation
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0003713 transcription coactivator activity
- GO:0004871 signal transducer activity
- GO:0010575 positive regulation vascular endothelial growth factor production
- GO:0046886 positive regulation of hormone biosynthetic process
- GO:0017162 aryl hydrocarbon receptor binding
- GO:0030528 transcription regulator activity
- View More GO Terms
- GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
- GO:0042789 mRNA transcription from RNA polymerase II promoter
- GO:0043193 positive regulation of gene-specific transcription
- GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
- GO:0045648 positive regulation of erythrocyte differentiation
- GO:0045821 positive regulation of glycolysis
- GO:0046982 protein heterodimerization activity
View more products with ARNT specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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