Arhgdib antibody

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Anti Arhgdib Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with ARHGDIB antibody (**VPA00730**) followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 1 second exposure. Arrow points to ARHGDIB (molecular weight 27 kDa).

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Rabbit anti Arhgdib

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Arhgdib

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Product Code Applications Pack Size List Price Your Price Qty

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VPA00730 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human ARHGDIB antibody recognizes the Rho GDP-dissociation inhibitor 2, also known as Rho GDI 2, rho GDP-dissociation inhibitor 2, or rho-GDI beta.

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (Scherle et al. 1993).

Rabbit anti Human ARHGDIB antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Rabbit anti ARHGDIB detects a band of approximately 27 kDa in THP-1 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: TRIS buffered glycine.
Preservative Stabilisers: 0.01% Thiomersal
<50% Glycerol
Immunogen: Recombinant protein encompassing part of the middle region of human ARHGDIB
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P52566
Entrez Gene: ARHGDIB
GO Terms: GO:0030036 actin cytoskeleton organization; GO:0005829 cytosol; GO:0005094 Rho GDP-dissociation inhibitor activity; GO:0005096 GTPase activator activity; GO:0005856 cytoskeleton; GO:0006928 cellular component movement; GO:0006955 immune response; GO:0007162 negative regulation of cell adhesion; GO:0007266 Rho protein signal transduction; View More GO Terms; GO:0007275 multicellular organismal development; GO:0016023 cytoplasmic membrane-bounded vesicle; GO:0051056 regulation of small GTPase mediated signal transduction