Rabbit anti ARF6 antibody recognizes human ADP-ribosylation factor 6 (encoded by ARF6). ARF6 is a small guanine nucleotide-binding protein and a member of the ADP-ribosylation factor family. ARF6 plays a vital role in the regulation of cytoskeleton organization and trafficking of vesicles.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to ARF6 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human ARF6
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
cellular component movement
small GTPase mediated signal transduction
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
regulation of Rac protein signal transduction
negative regulation of receptor-mediated endocytosis
regulation of dendritic spine development
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of ARF6 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti ARF6 antibody detects a band of approximately 20 kDa in cell lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available