Annexin V antibody
Rabbit anti Human annexin V antibody recognizes human annexin V (ANXA5), a member of the annexin family of membrane binding proteins that share structural properties and biological activities associated with membrane related processes. Annexin V, also known as placental anticoagulant protein 4, has potent anticoagulant properties and is amongst the annexins that have extracellular presence in addition to intracellular localization.
The annexin V protein binds with high affinity to membranes bearing phosphatidylserine (PS) and fluorescently labeled annexin V is commonly used as a marker for apoptotic cells in vitro and in vivo.
Rabbit anti Human annexin V antibody detects ANXA5 as a single band of 32 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
The annexin V protein binds with high affinity to membranes bearing phosphatidylserine (PS) and fluorescently labeled annexin V is commonly used as a marker for apoptotic cells in vitro and in vivo.
Rabbit anti Human annexin V antibody detects ANXA5 as a single band of 32 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti annexin V detects a band of approximately 32 kDa in HeLa cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Human ANXA5 full-length recombinant protein 6x His tagged.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08758
- Entrez Gene
- ANXA5
- GO Terms
- GO:0005509 calcium ion binding
- GO:0007596 blood coagulation
- GO:0004859 phospholipase inhibitor activity
- GO:0007165 signal transduction
- GO:0005544 calcium-dependent phospholipid binding
- GO:0005737 cytoplasm
- GO:0006916 anti-apoptosis
- GO:0050819 negative regulation of coagulation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Annexin V antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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