Androgen Receptor antibody

Rabbit anti Androgen Receptor

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Androgen Receptor

Product Code Applications Pack Size List Price Your Price Qty
AHP2430
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SDS Safety Datasheet SDS
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Rabbit anti androgen receptor antibody recognizes androgen receptor (AR), also known as the dihydrotestosterone receptor or nuclear receptor subfamily 3 group C member 4. Androgen receptor is a member of the steroid and nuclear receptor protein family. Androgen receptor is activated upon ligand binding and functions as a transcription factor transcribing androgen responsive genes.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to androgen receptor was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Synthetic peptide corresponding to amino acids 1-100 of the human androgen receptor.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/100
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti androgen receptor antibody detects two isoforms of androgen receptor at approximately 70 kDa and 99 kDa in 22RV-1 cell lysate and mouse tissue lysate under reducing conditions

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UniProt
P10275
Entrez Gene
AR
GO Terms
GO:0016049 cell growth
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005102 receptor binding
GO:0004882 androgen receptor activity
GO:0005497 androgen binding
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0006810 transport
GO:0007267 cell-cell signaling
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008219 cell death
GO:0008270 zinc ion binding
GO:0008283 cell proliferation
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010843 promoter binding
GO:0016563 transcription activator activity
GO:0019899 enzyme binding
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
GO:0046983 protein dimerization activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products