Aldehyde Dehydrogenase 1 antibody
Rabbit anti Human aldehyde dehydrogenase 1 antibody recognizes aldehyde dehydrogenase 1 also known as ALDH1.
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet (provided by RefSeq, Mar 2011).
Rabbit anti Human aldehyde dehydrongenase 1 antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet (provided by RefSeq, Mar 2011).
Rabbit anti Human aldehyde dehydrongenase 1 antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti aldehyde dehydrogenase 1 antibody recognizes a band of approximately 55 kDa in A549 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on immunogen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide directed corresponding to a C-terminal segment of human aldehyde dehydrogenase 1
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P00352
- Entrez Gene
- ALDH1A1
- GO Terms
- GO:0001758 retinal dehydrogenase activity
- GO:0004029 aldehyde dehydrogenase (NAD) activity
- GO:0005829 cytosol
- GO:0005099 Ras GTPase activator activity
- GO:0005497 androgen binding
- GO:0006069 ethanol oxidation
- GO:0006081 cellular aldehyde metabolic process
- GO:0006805 xenobiotic metabolic process
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of Aldehyde Dehydrogenase 1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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