Aldehyde Dehydrogenase 1 antibody

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Rabbit anti Aldehyde Dehydrogenase 1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00867
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human aldehyde dehydrogenase 1 antibody recognizes aldehyde dehydrogenase 1 also known as ALDH1.

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet (provided by RefSeq, Mar 2011).

Rabbit anti Human aldehyde dehydrongenase 1 antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti aldehyde dehydrogenase 1 antibody recognizes a band of approximately 55 kDa in A549 cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide directed corresponding to a C-terminal segment of human aldehyde dehydrogenase 1

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P00352
Entrez Gene
ALDH1A1
GO Terms
GO:0001758 retinal dehydrogenase activity
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0005829 cytosol
GO:0005099 Ras GTPase activator activity
GO:0005497 androgen binding
GO:0006069 ethanol oxidation
GO:0006081 cellular aldehyde metabolic process
GO:0006805 xenobiotic metabolic process
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Aldehyde Dehydrogenase 1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml