AKT3 antibody

Rabbit anti AKT3

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
AKT3

Product Code Applications Pack Size List Price Your Price Qty
AHP2997
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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Rabbit anti AKT3 antibody recognises RAC-gamma serine/threonine-protein kinase, also known as PKB gamma, RAC-gamma, and STK-2.

It plays a critical role in the AKT signalling pathway, and belongs to the AGC subfamily of protein kinases. AKT3 is involved in metabolism, cell survival, angiogenesis, and tumor formation (Baselga and Scaltriti. 2016). It is stimulated by insulin (Barthel et al. 1998), PDGF, and IGF1 (Sandirasegarane and Kester. 2001). AKT3 is a critical regulator of the growth of triple negative breast cancers (Chin et al. 2014).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to AKT3 was raised by repeated immunization of rabbits with highly purified antigen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 93-154 of human AKT3 (NP_859029.1)
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q9Y243
Entrez Gene
AKT3
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0004674 protein serine/threonine kinase activity
GO:0007165 signal transduction
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0006468 protein phosphorylation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products