AKT3 antibody

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Anti AKT3 Antibody gallery image 1 — Western blot analysis was performed by loading 25µg of various whole cell lysates probed with Rabbit anti AKT3 (**AHP2997**) at 1/3000 dilution. Arrow points to AKT3 (molecular weight 60 kDa).

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Rabbit anti AKT3

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: AKT3

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Product Code Applications Pack Size List Price Your Price Qty

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AHP2997 Datasheet Datasheet SDS SDS	WB	50 µl		Log in	Get Quote
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Rabbit anti AKT3 antibody recognises RAC-gamma serine/threonine-protein kinase, also known as PKB gamma, RAC-gamma, and STK-2.

It plays a critical role in the AKT signalling pathway, and belongs to the AGC subfamily of protein kinases. AKT3 is involved in metabolism, cell survival, angiogenesis, and tumor formation (Baselga and Scaltriti. 2016). It is stimulated by insulin (Barthel et al. 1998), PDGF, and IGF1 (Sandirasegarane and Kester. 2001). AKT3 is a critical regulator of the growth of triple negative breast cancers (Chin et al. 2014).

Target Species: Human
Product Form: Purified IgG - liquid
Antiserum Preparation: Antiserum to AKT3 was raised by repeated immunization of rabbits with highly purified antigen
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.02% Sodium Azide
50% Glycerol
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 93-154 of human AKT3 (NP_859029.1)
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Store at -20^oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/500	1/2000

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt: Q9Y243
Entrez Gene: AKT3
GO Terms: GO:0005886 plasma membrane; GO:0005515 protein binding; GO:0004674 protein serine/threonine kinase activity; GO:0007165 signal transduction; GO:0005524 ATP binding; GO:0005634 nucleus; GO:0005794 Golgi apparatus; GO:0006468 protein phosphorylation