ADRM1 antibody

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Rabbit anti ADRM1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00594
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human ADRM1 antibody recognizes the proteasomal ubiquitin receptor ADRM1, also known as 110 kDa cell membrane glycoprotein, proteasome regulatory particle non-ATPase 13, rpn13 homolog or Adhesion-regulating molecule 1.

ADRM1 gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of ADRM1 has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants (provided by RefSeq, Jul 2013).

Rabbit anti Human ADRM1 antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti ADRM1 detects a band of approximately 45 kDa in HeLa cell lysates.
Product Form
Purified IgG - liquid.
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose.
Immunogen
Synthetic peptide directed towards the C terminal region of human ADRM1

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
Q16186
Entrez Gene
ADRM1
GO Terms
GO:0000502 proteasome complex
GO:0002020 protease binding
GO:0005887 integral to plasma membrane
GO:0005624 membrane fraction
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0061133 endopeptidase activator activity
GO:0043248 proteasome assembly
GO:0070628 proteasome binding
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only.

Applications of ADRM1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml