Adipor2 antibody

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Goat anti Human Adipor2 (N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP1900 P WB 0.1 mg
Goat anti Human AdipoR2 antibody recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 2 (AdipoR2), a transmembrane protein and member of the ADIPOR family, expressed mainly in the liver and skeletal muscle, which acts a receptor for both globular and full-length adiponectin.

AdipoR2 acts as a mediator of fatty acid oxidation, glucose uptake by adiponectin and increased AMPK, PPARalpha ligand activity, thereby playing an important role in the regulation of glucose and lipid metabolism, and in oxidative stress.

Goat anti Human AdipoR2 is reported as suitable for use in immunocytochemistry on acetone fixed cells.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human AdipoR2 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin
Immunogen
Synthetic peptide CSRTPEPDIRLRKGHQLDGTRRGDNDSHQG corresponding to amino acids 11-40 within the N-terminal region of human AdipoR2.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
Q86V24 Related reagents
Entrez Gene
ADIPOR2 Related reagents
GO Terms
GO:0016021 integral to membrane
GO:0004872 receptor activity
GO:0009755 hormone-mediated signaling pathway
GO:0019395 fatty acid oxidation
GO:0042562 hormone binding
Regulatory
For research purposes only

Applications of Adipor2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/250
Western Blotting 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Liver and muscle

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
Antigen Retrieval Buffer, pH8.0 BUF025A 500 ml P
Antigen Retrieval Buffer, pH8.0 BUF025C 50 ml P

Product Specific References

References for Adipor2 antibody

  1. Shen, X. et al. (2012) Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs.
    Mol Cell Endocrinol. 363 (1-2): 27-35.