Adipor1 antibody

Goat anti Human Adipor1 (N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Adipor1
Region
(N-TERMINAL)

Product Code Applications Pack Size List Price Your Price Qty
AHP1824
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SDS Safety Datasheet SDS
P 0.1 mg loader
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Goat anti ADIPOR1 antibody recognizes human Adiponectin receptor protein 1, also known as ADIPOR1 or Adiponectin receptor protein 1. ADIPOR1 is a 375 amino acid ㅣ kDa multipass transmembrane protein and receptor for adiponectin (UniProt: Q96A54).

Goat anti ADIPOR1 antibody recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 1 . AdipoR1 is implicated in metabolic pathways, mediating increased fatty acid oxidation and glucose uptake by adiponectin. The expression of AdipoR1 in adipose tissue is decreased in obese humans, whilst weight loss results in increased expression.

Goat anti ADIPOR1 antibody is reported as suitable for use in immunocytochemistry of acetone fixed cells.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Broad Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to AdipoR1 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin.
Immunogen
Synthetic peptide SSHKGSVVAQGNGAPASNREADTVE corresponding to amino acids 2-26 within the N-terminal region of AdipoR1.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/250
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Liver and muscle

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References for Adipor1 antibody

  1. Shen X et al. (2012) Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs.
    Mol Cell Endocrinol. 363 (1-2): 27-35.

Synonyms
Adiponectin Receptor Protein 1
RRID
AB_2305062
UniProt
Q96A54
Entrez Gene
ADIPOR1
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0004872 receptor activity
GO:0009755 hormone-mediated signaling pathway
GO:0019395 fatty acid oxidation
GO:0019901 protein kinase binding
GO:0042562 hormone binding
View more products with ADIPOR1 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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