Adipor1 antibody

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Goat anti Human Adipor1 (N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP1824 P 0.1 mg
Goat anti ADIPOR1 antibody recognises human Adiponectin receptor protein 1, also known as ADIPOR1 or Adiponectin receptor protein 1. ADIPOR1 is a 375 amino acid ㅣ kDa multipass transmembrane protein and receptor for adiponectin (UniProt: Q96A54).

Goat anti ADIPOR1 antibody recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 1 . AdipoR1 is implicated in metabolic pathways, mediating increased fatty acid oxidation and glucose uptake by adiponectin. The expression of AdipoR1 in adipose tissue is decreased in obese humans, whilst weight loss results in increased expression.

AHP1824 is reported as suitable for use in immunocytochemistry of acetone fixed cells.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Broad Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to AdipoR1 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin.
Immunogen
Synthetic peptide SSHKGSVVAQGNGAPASNREADTVE corresponding to amino acids 2-26 within the N-terminal region of AdipoR1.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
Q96A54 Related reagents
Entrez Gene
ADIPOR1 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0004872 receptor activity
GO:0009755 hormone-mediated signaling pathway
GO:0019395 fatty acid oxidation
GO:0019901 protein kinase binding
GO:0042562 hormone binding
Regulatory
For research purposes only

Applications of Adipor1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/250
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Liver and muscle

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
Antigen Retrieval Buffer, pH8.0 BUF025A 500 ml P
Antigen Retrieval Buffer, pH8.0 BUF025C 50 ml P

Product Specific References

References for Adipor1 antibody

  1. Shen X et al. (2012) Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs.
    Mol Cell Endocrinol. 363 (1-2): 27-35.