ABCF1 antibody

Rabbit anti ABCF1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
ABCF1

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VPA00773
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Rabbit anti Human ABCF1 antibody recognizes ATP-binding cassette sub-family F member 1, also known as ATP-binding cassette 50 (TNF-alpha stimulated), ATP-binding cassette sub-family F member 1, TNF-alpha-stimulated ABC protein and TNFalpha-inducible ATP-binding protein.

The protein encoded by ABCF1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process (provided by RefSeq, Jul 2008).

Rabbit anti Human ABCF1 antibody detects a band of 110 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti ABCF1 antibody recognizes a band of approximately 110 kDa in NIH/3T3 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose
Immunogen
Synthetic peptide directed towards the N terminal region of human ABCF1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q8NE71
Entrez Gene
ABCF1
GO Terms
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0006413 translational initiation
GO:0006954 inflammatory response
GO:0008135 translation factor activity, nucleic acid binding
GO:0008494 translation activator activity
GO:0016887 ATPase activity
GO:0042788 polysomal ribosome
GO:0043022 ribosome binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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