14-3-3 Sigma antibody
Rabbit anti Human 14-3-3 sigma antibody recognizes the protein 14-3-3 sigma, also known as epithelial cell marker protein 1 or stratifin.
Hypermethylation of stratifin has been linked to early stages in breast cancer. Additionally, it has been shown to promote MMP-1 expression in fibroblasts.
Rabbit anti Human 14-3-3 sigma antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Hypermethylation of stratifin has been linked to early stages in breast cancer. Additionally, it has been shown to promote MMP-1 expression in fibroblasts.
Rabbit anti Human 14-3-3 sigma antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti 14-3-3 sigma detects a band of approximately 27 kDa in A431 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- KLH conjugated synthetic peptide of human 14-3-3 sigma (amino acids 222 - 248)
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P31947
- Entrez Gene
- SFN
- GO Terms
- GO:0001836 release of cytochrome c from mitochondria
- GO:0005615 extracellular space
- GO:0005634 nucleus
- GO:0005737 cytoplasm
- GO:0008426 protein kinase C inhibitor activity
- GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis
- GO:0019904 protein domain specific binding
- GO:0043154 negative regulation of caspase activity
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of 14-3-3 Sigma antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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