IL-1 Alpha antibody

Rabbit anti Bovine Interleukin-1 Alpha

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IL-1 Alpha

Product Code Applications Pack Size List Price Your Price Qty
AHP2373
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Bovine interleukin-1 alpha antibody recognizes bovine interleukin-1 alpha (IL-1α), an 18.8 kDa pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. It is secreted by activated macrophages and monocytes and is involved in the modulation of a wide range of immune and inflammatory responses.

IL-1α and the closely related IL-1β, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.

Target Species
Bovine
Species Cross-Reactivity
Target SpeciesCross Reactivity
Dolphin
Horse Weak
Rabbit
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to bovine interleukin-1alpha were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant bovine interleukin-1 alpha
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1ug/ml 5ug/ml
Western Blotting 0.1ug/ml 2ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product may be used as a capture antibody in a sandwich ELISA together with AHP2373B as the detection reagent. Recombinant Bovine interleukin-1alpha (PBP031) may be used as a standard.

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Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
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Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
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Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
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Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
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Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
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Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
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UniProt
P08831
Entrez Gene
IL1A
GO Terms
GO:0001660 fever generation
GO:0005829 cytosol
GO:0005125 cytokine activity
GO:0005149 interleukin-1 receptor binding
GO:0005507 copper ion binding
GO:0005615 extracellular space
GO:0006955 immune response
GO:0034605 cellular response to heat
GO:0046688 response to copper ion
GO:0051781 positive regulation of cell division
View more products with IL-1 ALPHA specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Bovine Products