Cortisol antibody

Rabbit anti Cortisol

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Cortisol

Product Code Applications Pack Size List Price Your Price Qty
2330-5010G
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 0.25 ml loader
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loader
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Rabbit anti cortisol antibody detects cortisol, a glucocorticoid that is produced by the adrenal cortex in response to pituitary adrenocorticotropic hormone (ACTH) stimulation. Cortisol is secreted into the plasma whereby the majority is bound to corticosteroid binding globulin (CBG) and serum albumin.

Cortisol is up-regulated in response to stress, and leads to an increase in blood pressure and blood sugar, and an immunosuppressive action to help restore body homeostasis. Cortisol also has multiple effects on human behaviour, including sleep patterns, mood, and the reception of sensory input.

Changes in cortisol expression have pathological consequences; hypercortisolism results in Cushing's syndrome, whilst hypocortisolism leads to Addison's disease.

Target Species
Broad
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to cortisol were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Cortisol-21-acetate-3-CMO-BSA
Approx. Protein Concentrations
IgG concentration 5.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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RRID
AB_1604897
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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