Cortisol antibody
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Rabbit anti cortisol antibody detects cortisol, a glucocorticoid that is produced by the adrenal cortex in response to pituitary adrenocorticotropic hormone (ACTH) stimulation. Cortisol is secreted into the plasma whereby the majority is bound to corticosteroid binding globulin (CBG) and serum albumin.
Cortisol is up-regulated in response to stress, and leads to an increase in blood pressure and blood sugar, and an immunosuppressive action to help restore body homeostasis. Cortisol also has multiple effects on human behaviour, including sleep patterns, mood, and the reception of sensory input.
Changes in cortisol expression have pathological consequences; hypercortisolism results in Cushing's syndrome, whilst hypocortisolism leads to Addison's disease.
Cortisol is up-regulated in response to stress, and leads to an increase in blood pressure and blood sugar, and an immunosuppressive action to help restore body homeostasis. Cortisol also has multiple effects on human behaviour, including sleep patterns, mood, and the reception of sensory input.
Changes in cortisol expression have pathological consequences; hypercortisolism results in Cushing's syndrome, whilst hypocortisolism leads to Addison's disease.
Product Details
- Target Species
- Broad
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to cortisol were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Immunogen
- Cortisol-21-acetate-3-CMO-BSA
- Approx. Protein Concentrations
- IgG concentration 5.0mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of Cortisol antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
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