Cortisol antibody

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Rabbit anti Cortisol

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
2330-5010G
Datasheet
E
MSDS
0.25 ml loader

Rabbit anti cortisol antibody detects cortisol, a glucocorticoid that is produced by the adrenal cortex in response to pituitary adrenocorticotropic hormone (ACTH) stimulation. Cortisol is secreted into the plasma whereby the majority is bound to corticosteroid binding globulin (CBG) and serum albumin.

Cortisol is up-regulated in response to stress, and leads to an increase in blood pressure and blood sugar, and an immunosuppressive action to help restore body homeostasis. Cortisol also has multiple effects on human behaviour, including sleep patterns, mood, and the reception of sensory input.

Changes in cortisol expression have pathological consequences; hypercortisolism results in Cushing's syndrome, whilst hypocortisolism leads to Addison's disease.

Product Details

Target Species
Broad
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to cortisol were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Cortisol-21-acetate-3-CMO-BSA
Approx. Protein Concentrations
IgG concentration 5.0mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
18 months from date of despatch.

More Information

Regulatory
For research purposes only

Applications of Cortisol antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B C E P WB 1 ml loader
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Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg