Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes myelin/oligodendrocyte-specific protein (MOSP), a ~48 kDa membrane protein expressed exclusively in oligodendrocytes (Mu and Dyer 1994). In rat neonates Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes oligodendrocytes but does not label type 1 astrocytes. Mouse anti Rat CNS myelin antibody, clone CE-1 also recognizes CNS myelin and oligodendrocytes, and does not cross react with peripheral myelin.
N.B. Antibody reactivity and working conditions may vary between species.
Ascitic Fluid - raw
Rat glial membranes and whole brain white matter.
Approx. Protein Concentrations
Reagents In The Kit
Preparing The Antibody
Spleen cells from immunized mice were fused with cells of the AG8 murine myeloma.
Store at -20oC only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
12 months from date of despatch.
For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
1. Dyer, C.A. et al. (1991) Myelin/oligodendrocyte-specific protein: a novel surface membrane protein that associates with microtubules.J Neurosci Res. 28 (4): 607-13.
1. Dyer, C.A. & Matthieu, J.M. (1994) Antibodies to myelin/oligodendrocyte-specific protein and myelin/oligodendrocyte glycoprotein signal distinct changes in the organization of cultured oligodendroglial membrane sheets.J Neurochem. 62 (2): 777-87.