Image legend: Staining of WEHI cells with RAT ANTI-MOUSE CD34:RPE (MCA1825PE).
CD31 (PECAM) (MCA2388), expressed on endothelial cells, platelets and most leukocyte populations. The primary ligand is avß3 integrin, but it also binds in a homophilic manner.
CD49a (a1 integrin) (MCA2301), expressed on activated T lymphocytes and monocytes, associates with the ß1 intergrin subunit to form CD49a/CD29 (VLA-1).
Image legend: Staining of mouse peripheral blood lymphocytes with RAT ANTI-MOUSE CD49d : Alexa Fluor® 488 (MCA2294A488).
CD54 (ICAM-1) (MCA1371) is expressed on T cells, B cells, monocytes, and endothelial cells. It is ligand for LFA-1.
CD102 (ICAM-2) (MCA2295) is broadly expressed on most leukocytes and is constitutively expressed on endothelial cells. It is the ligand for LFA-1.
CD106 (VCAM-1) (MCA2297), expressed predominantly on endothelial cells, up-regulated during inflammation; binds CD49d.
CD107b (MAC-3 or LAMP-2) (MCA2293) is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. As expression is predominantly cytoplasmic, flow cytometry analysis can be improved by using Leucoperm™.
CD147 (Basigin) (MCA2283) is found on leukocytes, red cells, platelets, and endothelial cells. CD147 binds to itself or a3ß1.
MAdCAM-1 (MCA1551) is expressed on endothelial cells within the mesenteric lymph nodes and the lamina propria of the intestine. It binds integrin a4ß7 and CD62L.