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IL-6 Antibody | 6B4 IGH 54

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  • Rat anti Mouse Interleukin-6:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    6B4 IGH 54
  • Isotype
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2794ZE, FNdatasheet pdfdatasheet pdf0.1 mg
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    • Rat anti Mouse Interleukin-6 antibody, clone 6B4 IGH 54recognizes mouse IL-6 (interleukin-6), a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts acts as the primary inducer of the acute phase response in the liver.

      IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130). IL-6 can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.

      Rat anti Mouse Interleukin-6 antibody, clone 6B4 IGH 54 can be used to neutralize the activity of 50pg/ml of recombinant mouse IL-6 by >95% in a functional assay.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Functional Assays3ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional IL-6 Antibody Formats

    Formats Clone Applications Sizes available
    IL-6 Antibody : Preservative Free 6B4 IGH 54 E, FN 0.1 mg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
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      Rabbit F(ab')2 anti Rat IgG:Dylight®800STAR16D800GA0.1 mgF, IF, WB
      Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed)STAR71D800GA0.1 mgF, IF, WB
      Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed)STAR690.5 mlF
      Rabbit F(ab')2 anti Rat IgG:FITCSTAR17B1 mgF
      Goat anti Rat IgG:HRP (Mouse Adsorbed)STAR720.5 mgC, E, P
      Rabbit F(ab')2 anti Rat IgG:HRPSTAR21B1 mgC, E, P, RE
      Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed)STAR730.5 mlF
      Rabbit F(ab')2 anti Rat IgG:RPESTAR20A1 mlF

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              Further Reading

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