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ABCA1 Antibody | 3A1-891.3

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ABCA1 Antibody | 3A1-891.3 gallery image 1

Staining of pCPT-cAMP stimulated RAW264.7 cells with Rat anti Mouse ABCA (MCA2878)

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ABCA1 Antibody | 3A1-891.3 gallery image 2

Staining of pCPT-cAMP stimulated RAW264.7 cells with Rat anti Mouse ABCA1:FITC (MCA2878F)

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  • ABCA1 Antibody | 3A1-891.3 thumbnail image 1
  • ABCA1 Antibody | 3A1-891.3 thumbnail image 2
  • Rat anti Mouse ABCA1:FITC

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  • Product Type
    Monoclonal Antibody
  • Clone
    3A1-891.3
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2878FFdatasheet pdfdatasheet pdf0.1 mg
    MCA2878F
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Rat anti Mouse ABCA1 antibody, clone 3A1-891.3 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease.

      Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Flow CytometryNeat1/10

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • Flow Cytometry
      Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional ABCA1 Antibody Formats

    Formats Clone Applications Sizes available
    ABCA1 Antibody : FITC 3A1-891.3 F 0.1 mg
    • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

    Recommended Secondary Antibody

      Recommended Negative Isotype Control

        DescriptionProduct CodePack SizeApplicationsList PriceQuantity
        Rat IgG1 Negative Control:FITCMCA1211F100 TestsF
        MCA1211F

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          Mouse Seroblock FcRBUF041A0.1 mgF
          BUF041A
          Mouse Seroblock FcRBUF041B0.5 mgF
          BUF041B

          Recommended Positive Controls

            Histology Controls

              References

              1. Zarubica, A. et al. (2007) ABCA1, from pathology to membrane function.
              Pflugers Arch. 453 (5): 569-79.

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