Vaccinia Virus antibody | TV43
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Mouse anti Vaccinia Virus antibody, clone TV43 recognizes the Vaccinia virus, a large poxvirus. Poxviruses are DNA viruses that replicate in the cytoplasm of the host cell and therefore need a large genome to encode for the various proteins involved in DNA replication and transcription. Vaccinia virus infection is very mild and generally causes no symptoms in healthy individuals. Vaccinia infection initiates immune responses that also protects against smallpox, a much more severe disease with a high mortality rate. Vaccinia is best known for its use as a vaccine against smallpox, which was officially declared eradicated in 1979 (Breman & Arita 1980). There is some concern that smallpox might be re-introduced as a biological weapon, as such it might still pose a threat to humanity (Tegnell et al. 2002).
Mouse anti Vaccinia Virus antibody, clone TV43 recognizes a ~27 kDa protein in Western blotting of the following viruses: Vaccinia virus strain Elstree, Ectromelia virus strain K-1, Cowpox virus strain Grishak. It might also recognize the same protein in the Smallpox virus.
Mouse anti Vaccinia Virus antibody, clone TV43 recognizes a ~27 kDa protein in Western blotting of the following viruses: Vaccinia virus strain Elstree, Ectromelia virus strain K-1, Cowpox virus strain Grishak. It might also recognize the same protein in the Smallpox virus.
Product Details
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Live dry smallpox vaccine.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of Vaccinia Virus antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | |||
| Western Blotting |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Western Blotting
- MCA2833 detects a band of approximately 27kDa under non-reducing conditions.
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