Mouse anti Rat serotonin transporter antibody, clone 2D7/3 reacts with the serotonin transporter, also known as Sodium-dependent serotonin transporter, 5HT transporter or Solute carrier family 6 member 4. Serotonin transporter is a 630 amino acid ~70 kDa multiple pass endosomal membrane protein. Serotonin transporter is involved in the transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization and in regulating availability of serotonin to receptors of the serotonergic system.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Rat serotonin transporter, N-terminus/GST fusion protein (aa 1-85).
- Approx. Protein Concentrations
- 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Serotonin Transporter antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Not recommended for use in Western blotting.
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Secondary Antibodies Available