Reticulum Cells antibody | ED11

Biochemical analysis has revealed that Mouse anti Rat reticulum cells antibody, clone ED11 recognizes complement factor C3. In vivo studies have shown that Mouse anti Rat reticulum cells antibody, clone ED11 blocks immune complex trapping on follicular dendritic cells (Van den Berg et al. 1992).
Product Details
- Target Species
- Rat
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide - Carrier Free
- Yes
- Immunogen
- Rat spleen cell homogenate.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with the mouse SP2/0.Ag14 myeloma cell line.
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of Reticulum Cells antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Flow Cytometry | |||
Immunohistology - Frozen 1 | 1/100 | 1/300 | |
Immunohistology - Paraffin |
- 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
Secondary Antibodies Available
Negative Isotype Controls Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA1209 | F | 0.1 mg |
![]() |
Product Specific References
Source Reference
-
Van den Berg, T.K. et al. (1989) The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies.
Eur J Immunol. 19 (9): 1747-56.
References for Reticulum Cells antibody
-
Van den Berg, T.K. et al. (1992) Selective inhibition of immune complex trapping by follicular dendritic cells with monoclonal antibodies against rat C3.
Eur J Immunol. 22 (4): 957-62. -
Sato K et al. (2001) Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants.
J Immunol. 166 (6): 4185-94. -
Lin, Y. et al. (1999) Rejection of cardiac xenografts by CD4+ or CD8+ T cells.
J Immunol. 162 (2): 1206-14. -
Sato, K. et al. (1999) Suppression of delayed xenograft rejection by specific depletion of elicited antibodies of the IgM isotype.
Transplantation. 68 (6): 844-54. -
Molleví, D.G. et al. (2001) Heart and liver xenotransplantation under low-dose tacrolimus: graft survival after withdrawal of immunosuppression.
Transplantation. 71 (2): 217-23.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra