Mouse anti Rat CD26 antibody, clone OX-61
recognizes CD26, rat liver antigen dipeptidyl peptidase IV. Reacts with liver bile canicular domains and brush borders of bile ducts. It also recognizes other epithelial brush borders such as a kidney and intestine, MRC OX-61 recognizes T lymphocytes and some B lymphocytes.
Mouse anti Rat CD26 antibody, clone OX-61 has been reported as being suitable for use in Western blotting (McCaughan et al. 1990
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Carrier Free
- 110 kDa membrane glycoprotein
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised mice were fused with cells of the PS-NSI/1Ag4-1 mouse myeloma cell line.
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
regulation of T cell mediated immunity
serine-type endopeptidase activity
integral to membrane
positive regulation of cell proliferation
negative regulation of extracellular matrix disassembly
apical plasma membrane
T cell costimulation
protein homodimerization activity
endothelial cell migration
establishment of localization
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD26 antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul. Method sheets available on request.
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Negative Isotype Controls Available
Application Based External Images
Product Specific References
References for CD26 antibody
McCaughan, G.W. et al. (1990) Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence.
Hepatology. 11 (4): 534-44.
Cohen, D. et al. (2004) Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells.
Proc Natl Acad Sci U S A. 101 (38): 13792-7.
Korom S et al. (1997) Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients.
Transplantation. 63 (10): 1495-500.
Kraml J et al. (2003) Glucocorticoid agonistic and antagonistic effects of mifepristone and onapristone on thymocyte subset composition and CD26/dipeptidyl peptidase IV activity in infant male rats.
J Steroid Biochem Mol Biol. 87 (1): 85-96.
Cohen D et al. (2007) Par1b promotes hepatic-type lumen polarity in Madin Darby canine kidney cells via myosin II- and E-cadherin-dependent signaling.
Mol Biol Cell. 18 (6): 2203-15.
László, V. et al. (2008) Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes.
Histochem Cell Biol. 130 (5): 1005-14.
Skripuletz T et al. (2007) Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma.
Am J Physiol Lung Cell Mol Physiol. 292 (6): L1564-71.
Molina-Jijón E et al. (2015) All-trans retinoic acid prevents oxidative stress-induced loss of renal tight junction proteins in type-1 diabetic model.
J Nutr Biochem. 26 (5): 441-54.
Trujillo, J. et al. (2016) Curcumin prevents cisplatin-induced decrease in the tight and adherens junctions: relation to oxidative stress.
Food Funct. 7 (1): 279-93.
Paku, S. et al. (2004) 2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies.
Hepatology. 39 (5): 1353-61.
Santoyo-Sánchez MP et al. (2013) Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.
BMC Nephrol. 14: 211.
Molina-Jijón, E. et al. (2017) Aldosterone signaling regulates the over-expression of claudin-4 and -8 at the distal nephron from type 1 diabetic rats.
PLoS One. 12 (5): e0177362.