Mouse anti Rat beta 2 Microglobulin antibody, clone TLD-3H12B recognizes native beta 2 microglobulin which is a component of MHC class I molecules, which are present on all nucleated cells. Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Carrier Free
- Rat microglial cells.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the mouse MOM myeloma cell line.
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
antigen processing and presentation of peptide antigen via MHC class I
MHC class I protein complex
response to drug
response to cadmium ion
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Beta 2 Microglobulin antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
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Secondary Antibodies Available
Negative Isotype Controls Available
Product Specific References
References for Beta 2 Microglobulin antibody
Loconto, J. et al. (2003) Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules.
Cell. 112: 607 - 618.
Aktaş, A. et al. (2013) Ankaferd-Induced Early Soft Tissue Wound Healing in an Experimental Rat Model
Turkiye Klinikleri Journal of Medical Sciences. 33 (6): 1344-53.
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