Plasmodium vivax CSP antibody | PVC-1
Mouse anti Plasmodium vivax CSP antibody, clone PVC-1 recognizes the circumsporozoite protein (CSP) of Plasmodium vivax. Outside sub-Saharan Africa, where P. falciparum infection is most common, P. vivax is the most common cause of malaria infection. While not as deadly as P. falciparum, it does negatively affect human health. Malaria infection is initiated when an infected Anopheles mosquito injects sporozoites into a person’s blood during a blood meal. The sporozoites migrate to and infect hepatocytes where they multiply asexually. The CSP is the major surface protein of sporozoites and form a dense coat on the parasite’s surface. The CSP is involved in the motility of the sporozoite and the invasion of target cells. It is also required for sporozoite development in the mosquito. The protein has been extensively studied as a vaccine candidate. Vaccination with irradiated sporozoites has been shown to protect against malarial parasites with the sera of protected individuals recognising CSP.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- For research purposes only
Applications of Plasmodium vivax CSP antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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