Myelin antibody | CE-1 (4A9)

100% Secure

Mouse anti Myelin (Oligodendrocytes+Cns)

Product Type
Monoclonal Antibody
Clone
CE-1 (4A9)
Isotype
IgM
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
6418-0606 C 0.1 ml
Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes myelin/oligodendrocyte-specific protein (MOSP), a ~48 kDa membrane protein expressed exclusively in oligodendrocytes (Mu and Dyer 1994). In rat neonates Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes oligodendrocytes but does not label type 1 astrocytes. Mouse anti Rat CNS myelin antibody, clone CE-1 also recognizes CNS myelin and oligodendrocytes, and does not cross react with peripheral myelin.

Product Details

Species Cross-Reactivity
Target SpeciesCross Reactivity
Chicken
Ferret
Rat
Human
Monkey
Mouse
Cat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Ascitic Fluid - raw
Preservative Stabilisers
None present
Immunogen
Rat glial membranes and whole brain white matter.
Fusion Partners
Spleen cells from immunized mice were fused with cells of the AG8 murine myeloma.

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch.

More Information

Regulatory
For research purposes only

Applications of Myelin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Rat brain

Product Specific References

Source Reference

  1. Dyer, C.A. et al. (1991) Myelin/oligodendrocyte-specific protein: a novel surface membrane protein that associates with microtubules.
    J Neurosci Res. 28 (4): 607-13.

References for Myelin antibody

  1. Dyer, C.A. & Matthieu, J.M. (1994) Antibodies to myelin/oligodendrocyte-specific protein and myelin/oligodendrocyte glycoprotein signal distinct changes in the organization of cultured oligodendroglial membrane sheets.
    J Neurochem. 62 (2): 777-87.
  2. Mu, Q.Q. & Dyer, C. (1994) Developmental expression of MOSP in cultured oligodendrocytes.
    Neurochem Res. 19 (8): 1033-8.