Myelin antibody | CE-1 (4A9)
Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes myelin/oligodendrocyte-specific protein (MOSP), a ~48 kDa membrane protein expressed exclusively in oligodendrocytes (Mu and Dyer 1994). In rat neonates Mouse anti Rat CNS myelin antibody, clone CE-1 recognizes oligodendrocytes but does not label type 1 astrocytes. Mouse anti Rat CNS myelin antibody, clone CE-1 also recognizes CNS myelin and oligodendrocytes, and does not cross react with peripheral myelin.
- Species Cross-Reactivity
Target Species Cross Reactivity Chicken Ferret Rat Human Monkey Mouse Cat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Ascitic Fluid - raw
- Preservative Stabilisers
- None present
- Rat glial membranes and whole brain white matter.
- Fusion Partners
- Spleen cells from immunized mice were fused with cells of the AG8 murine myeloma.
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- For research purposes only
Applications of Myelin antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Rat brain
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Product Specific References
Dyer, C.A. et al. (1991) Myelin/oligodendrocyte-specific protein: a novel surface membrane protein that associates with microtubules.
J Neurosci Res. 28 (4): 607-13.
References for Myelin antibody
Dyer, C.A. & Matthieu, J.M. (1994) Antibodies to myelin/oligodendrocyte-specific protein and myelin/oligodendrocyte glycoprotein signal distinct changes in the organization of cultured oligodendroglial membrane sheets.
J Neurochem. 62 (2): 777-87.
Mu, Q.Q. & Dyer, C. (1994) Developmental expression of MOSP in cultured oligodendrocytes.
Neurochem Res. 19 (8): 1033-8.