IDO antibody | mIDO-48

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Rat anti Mouse IDO

Product Type
Monoclonal Antibody
Clone
mIDO-48
Isotype
IgG2b
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA6067GA WB 0.1 mg
Rat anti Mouse IDO, clone mIDO-48 recognizes IDO also known as indolamine 2,3-dioxygenase. IDO is a ubiquitously expresesd cytoplasmic enzyme that catalyzes the degradation of the essential amino acid L-tryptophan. IDO is implicated in protective response against both intracellular and extracellular pathogens. IDO is one of a number of genes induced by interferon gamma.

Product Details

Target Species
Mouse
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant mouse IDO protein
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch

More Information

UniProt
P28776 Related reagents
Entrez Gene
Ido1 Related reagents
GO Terms
GO:0002534 cytokine production involved in inflammatory response
GO:0002666 positive regulation of T cell tolerance induction
GO:0002678 positive regulation of chronic inflammatory response
GO:0002830 positive regulation of type 2 immune response
GO:0004833 tryptophan 2,3-dioxygenase activity
GO:0055114 oxidation-reduction process
GO:0007610 behavior
GO:0019441 tryptophan catabolic process to kynurenine
GO:0020037 heme binding
GO:0030485 smooth muscle contractile fiber
GO:0032421 stereocilium bundle
GO:0032496 response to lipopolysaccharide
GO:0032693 negative regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0033555 multicellular organismal response to stress
GO:0033754 indoleamine 2,3-dioxygenase activity
GO:0034276 kynurenic acid biosynthetic process
GO:0043065 positive regulation of apoptosis
GO:0046007 negative regulation of activated T cell proliferation
GO:0070233 negative regulation of T cell apoptosis
Regulatory
For research purposes only

Applications of IDO antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 2.0 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) STAR131A 1 ml C E P WB
Goat anti Rat IgG:Biotin (Mouse Adsorbed) STAR131B 0.5 mg C E IF P WB
Rabbit F(ab')2 anti Rat IgG:Dylight®800 STAR16D800GA 0.1 mg F IF WB
Rabbit F(ab')2 anti Rat IgG:FITC STAR17B 1 mg F
Rabbit F(ab')2 anti Rat IgG:HRP STAR21B 1 mg C E P RE
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) STAR69 0.5 ml F
Goat anti Rat IgG:DyLight®649 (Mouse Adsorbed) STAR71D649GA 0.1 mg F IF
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) STAR71D800GA 0.1 mg F IF WB
Goat anti Rat IgG:HRP (Mouse Adsorbed) STAR72 0.5 mg C E P
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) STAR73 0.5 ml F