CD5 antibody | 53-7.3
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Rat anti Mouse CD5
- Product Type
- Monoclonal Antibody
- Clone
- 53-7.3
- Isotype
- IgG2a
- Specificity
- CD5
Antibody Quality and 
Unrivaled 
| Rat anti Mouse CD5 recognizes the CD5 cell surface glycoprotein. CD5 is a 67 kDa member of the scavenger receptor cysteine-rich protein superfamily. CD5 is primarily expressed on an IgM subset of B cells and alpha/beta T cells showing very little expression on gamma delta T cells. CD5 is also expressed by tumor cells in cases of B Cell Chronic Lymphocytic Leukaemia (B-CLL). The role for CD5 involves its interactions with antigen receptors on both T cells and B cells although the precise function has not been elucidated. The ability of CD5 to inhibit TCR signaling implies that it is important in T cell development and activation. |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Mouse thymus or spleen
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/5 | 1/20 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10 μl of the suggested working dilution to label 1x106 cells in 100ul
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Rat IgG2a Negative Control | MCA1212 | E F | 1 ml |
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| List Price | Your Price | ||||||
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| Description | Rat IgG2a Negative Control | ||||||
- UniProt
- P06127
- Entrez Gene
- CD5
- GO Terms
- GO:0005044 scavenger receptor activity
- GO:0005887 integral to plasma membrane
- GO:0008037 cell recognition
- GO:0008283 cell proliferation
View more products with CD5 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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