CD5 antibody | 53-7.3

Rat anti Mouse CD5
- Product Type
- Monoclonal Antibody
- Clone
- 53-7.3
- Isotype
- IgG2a
- Specificity
- CD5
Rat anti Mouse CD5 recognizes the CD5 cell surface glycoprotein. CD5 is a 67 kDa member of the scavenger receptor cysteine-rich protein superfamily. CD5 is primarily expressed on an IgM subset of B cells and alpha/beta T cells showing very little expression on gamma delta T cells. CD5 is also expressed by tumor cells in cases of B Cell Chronic Lymphocytic Leukaemia (B-CLL). The role for CD5 involves its interactions with antigen receptors on both T cells and B cells although the precise function has not been elucidated. The ability of CD5 to inhibit TCR signaling implies that it is important in T cell development and activation. |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Mouse thymus or spleen
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | ![]() |
1/5 | 1/20 |
- Flow Cytometry
- Use 10 μl of the suggested working dilution to label 1x106 cells in 100ul
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Rat IgG2a Negative Control | MCA1212 | E F | 1 ml |
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List Price | Your Price | ||||||
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Description | Rat IgG2a Negative Control |
- UniProt
- P06127
- Entrez Gene
- CD5
- GO Terms
- GO:0005044 scavenger receptor activity
- GO:0005887 integral to plasma membrane
- GO:0008037 cell recognition
- GO:0008283 cell proliferation
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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