CD252 antibody | OX-89
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C ResetRat anti Mouse CD252
- Product Type
- Monoclonal Antibody
- Clone
- OX-89
- Isotype
- IgG1
- Specificity
- CD252
Antibody Quality and Performance Guarantee
| Rat anti Mouse CD252 antibody, clone OX-89 recognizes mouse OX40 (CD134) ligand, which is otherwise known as CD252. CD252 expression has been shown to be restricted to activated dendritic cells, B cells and vascular endothelium. Rat anti Mouse CD252 antibody, clone OX-89 has been reported to inhibit OX40/OX40L interaction (Malström et al. 2001). |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Rat CD4 and mouse CD134 ligand Chimaeric protein.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunized PVG rats were fuzed with cells of the NS1 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
||
| Immunohistology - Frozen | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
References for CD252 antibody
-
Malmström V et al. (2001) CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice.
J Immunol. 166 (11): 6972-81.
- Synonyms
- OX40 Ligand
- RRID
- AB_2207377
- UniProt
- P43488
- Entrez Gene
- Tnfsf4
- GO Terms
- GO:0016021 integral to membrane
- GO:0005125 cytokine activity
- GO:0005164 tumor necrosis factor receptor binding
- GO:0005615 extracellular space
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0008203 cholesterol metabolic process
- GO:0032582 negative regulation of gene-specific transcription
- GO:0043433 negative regulation of transcription factor activity
- View More GO Terms
- GO:0050710 negative regulation of cytokine secretion
- GO:0051024 positive regulation of immunoglobulin secretion
MCA1881
150702
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with CD252 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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