CD21/CD35 antibody | 7E9
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Rat anti Mouse CD21/CD35:FITC
- Product Type
- Monoclonal Antibody
- Clone
- 7E9
- Isotype
- IgG2a
- Specificity
- CD21/CD35
Antibody Quality and Performance Guarantee
| Rat anti Mouse CD21/CD35, clone 7E9 recognizes CD21/CD35 also known as CR2/CR1. CD21, also known as complement receptor 2 (CR2) and CD35, also known as complement receptor 1 (CR1) bind the activated products of C3 and C4. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages and activated granulocytes and they constitute the principle receptors for uptake and retention of immune complexes. In their absence, memory B-cell survival is markedly impaired. |
- Target Species
- Mouse
- Product Form
- Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- CD35/CFA
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) FITC 490 525 - Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/20 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10 μl of the suggested working dilution to label 1x106 cells in 100ul
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Rat IgG2a Negative Control:FITC | MCA1212F | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Rat IgG2a Negative Control:FITC | ||||||
References for CD21/CD35 antibody
-
Kulik, L. et al. (2015) A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
Mol Immunol. 63 (2): 479-88.
- UniProt
- P19070
- Entrez Gene
- Cr2
- GO Terms
- GO:0016021 integral to membrane
- GO:0004875 complement receptor activity
- GO:0006958 complement activation, classical pathway
- GO:0009897 external side of plasma membrane
- GO:0042113 B cell activation
- GO:0045087 innate immune response
View more products with CD21 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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