CD19/CD3 | 6D5/KT3
Rat anti Mouse CD19:FITC/CD3:RPE
- Product Type
- Dual Color Reagent
- Clone
- 6D5/KT3
- Isotype
- Cocktail
- Specificity
- CD19/CD3
Rat anti Mouse CD19:FITC/CD3:RPE dual color reagent is a dual colour reagent recognising mouse CD19 and CD3. Clone 6D5 recognises murine CD19, a ~95 kDa cell surface glycoprotein expressed by B lymphocytes. Clone KT3 recognises murine CD3, a cell surface glycoprotein expressed by mature T cells. |
- Target Species
- Mouse
- Product Form
- Dual Colour combination consisting of FITC conjugated and RPE conjugated monoclonal antibodies mixed in optimal ratio - lyophilized
- Reconstitution
- Reconstitute with 1 ml distilled water
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide 1% Bovine Serum Albumin 5% Sucrose - Antibody Isotypes
- FITC reagent: IgG2a (RAT)
RPE reagent: IgG2a (RAT) - Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) FITC 490 525 RPE 488nm laser 496 578 RPE 561nm laser 546 578 - Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | Neat |
References for CD19/CD3
-
Tomonari, K. (1988) A rat antibody against a structure functionally related to the mouse T-cell receptor/T3 complex.
Immunogenetics. 28 (6): 455-8. -
Stables, M.J. et al. (2010) Priming innate immune responses to infection by cyclooxygenase inhibition kills antibiotic-susceptible and -resistant bacteria.
Blood. 116 (16): 2950-9. -
Suszko, A. & Obmińska-Mrukowicz B (2013) Influence of polysaccharide fractions isolated from Caltha palustris L. on the cellular immune response in collagen-induced arthritis (CIA) in mice. A comparison with methotrexate.
J Ethnopharmacol. 145 (1): 109-17. -
Drynda, A. et al. (2016) Immunoregulatory effects of 4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)-thiosemicarbazide (06K) in non-immunized and SRBC-immunized mice.
J Pharm Pharmacol. 68 (12): 1613-20. -
Zimecki, M. et al. (2015) Immune function in cyclophosphamide-treated mice is restored by the T-cell-tropic isoxazole derivative R-13.
J Immunotoxicol. 12 (4): 322-9. -
Piekarska, J. et al. (2018) Effects of iridoid-anthocyanin extract of Cornus mas L. on hematological parameters, population and proliferation of lymphocytes during experimental infection of mice with Trichinella spiralis.
Exp Parasitol. 188: 58-64. -
Piekarska, J. et al. (2022) Evaluation of Immunotropic Activity of Iridoid-Anthocyanin Extract of Honeysuckle Berries (Lonicera caerulea L.) in the Course of Experimental Trichinellosis in Mice.
Molecules. 27 (6): 1949. -
Szczypka, M. et al. (2020) Selegiline and clomipramine effects on lymphocyte subsets, regulatory T cells and sheep red blood cell (SRBC)-induced humoral immune response after in vivo administration in mice.
Eur J Pharmacol. 887: 173560.
View The Latest Product References
- RRID
- AB_324076
- UniProt
- P11942
- P29020
- P24161
- P25918
- P22646
- P04235
- Entrez Gene
- Cd3d
- Cd3g
- Cd3e
- Cd247
- Cd19
- Cd247
- GO Terms
- GO:0016021 integral to membrane
- GO:0004888 transmembrane receptor activity
- GO:0006461 protein complex assembly
- GO:0007166 cell surface receptor linked signaling pathway
- GO:0042105 alpha-beta T cell receptor complex
- GO:0045059 positive thymic T cell selection
- GO:0007163 establishment or maintenance of cell polarity
- GO:0015031 protein transport
- GO:0042981 regulation of apoptosis
- View More GO Terms
- GO:0046982 protein heterodimerization activity
- GO:0001772 immunological synapse
- GO:0002669 positive regulation of T cell anergy
- GO:0008624 induction of apoptosis by extracellular signals
- GO:0009897 external side of plasma membrane
- GO:0032729 positive regulation of interferon-gamma production
- GO:0032753 positive regulation of interleukin-4 production
- GO:0045060 negative thymic T cell selection
- GO:0045086 positive regulation of interleukin-2 biosynthetic process
- GO:0045879 negative regulation of smoothened signaling pathway
- GO:0046641 positive regulation of alpha-beta T cell proliferation
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
- GO:0050850 positive regulation of calcium-mediated signaling
- GO:0050852 T cell receptor signaling pathway
- GO:0005515 protein binding
- GO:0050853 B cell receptor signaling pathway
DC035
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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