CD120a antibody | HM104

Rat anti Mouse CD120a:RPE
- Product Type
- Monoclonal Antibody
- Clone
- HM104
- Isotype
- IgG2a
- Specificity
- CD120a
Rat anti Mouse CD120a antibody, clone HM104 recognizes an extracellular region of mouse CD120a, also known as TNF receptor type I (TNFR1). TNFR1 is an ubiquitously expressed transmembrane glycoprotein and member of the tumor necrosis factor receptor (TNFR) superfamily, which plays a key role in regulating the inflammatory response, acting as a receptor for tumor necrosis factor alpha (TNF-alpha) and lymphotoxin-alpha (TNF-beta). CD120a also plays a role in apoptosis, cytokine induction, cell differentiation, tumor necrosis and early stages of graft-versus-host disease, and its soluble form sTNFR1, acts as an inhibitor of TNF-alpha induced responses by acting as a decoy receptor. |
- Target Species
- Mouse
- Product Form
- Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
- Preparation
- Purified IgG prepared by ion exchange chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Pack Size: 100 Tests<0.1% sodium azide (NaN3)
0.2% bovine serum albuminPack Size: 25 Tests<0.1% sodium azide (NaN3)
0.5% bovine serum albumin - Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) RPE 488nm laser 496 578 - Regulatory
- For research purposes only
- Guarantee
- 6 months from date of despatch
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
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Flow Cytometry | ![]() |
Neat |
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Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Mouse Seroblock FcR | BUF041A | F | 0.1 mg |
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Mouse Seroblock FcR | BUF041B | F | 0.5 mg |
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Description | Mouse Seroblock FcR |
References for CD120a antibody
-
Pearl-Yafe, M. et al. (2010) Tumor necrosis factor receptors support murine hematopoietic progenitor function in the early stages of engraftment.
Stem Cells. 28 (7): 1270-80. -
Nakagawa, J. et al. (2007) TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma.
Int J Oncol. 30 (4): 803-11. -
Li, P. et al. (2023) TNFR2 deficiency impairs the growth of mouse colon cancer
Int J Biol Sci.19 (4): 1024-35.
- Synonyms
- TNF Receptor Type I
- RRID
- AB_323589
- UniProt
- P25118
- Entrez Gene
- Tnfrsf1a
- GO Terms
- GO:0005886 plasma membrane
- GO:0042742 defense response to bacterium
- GO:0006915 apoptosis
- GO:0016021 integral to membrane
- GO:0005031 tumor necrosis factor receptor activity
- GO:0006693 prostaglandin metabolic process
- GO:0006954 inflammatory response
- GO:0045121 membrane raft
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- View More GO Terms
- GO:0050729 positive regulation of inflammatory response
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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