Catenin Alpha 1 antibody | alpha-CAT-7A4
Mouse anti Catenin Alpha 1
- Product Type
- Monoclonal Antibody
- Clone
- alpha-CAT-7A4
- Isotype
- IgG1
- Specificity
- Catenin Alpha 1
Antibody Quality and Performance Guarantee
| Mouse anti catenin alpha 1 antibody clone alpha-CAT-7A4 recognizes catenin alpha 1 also known as alpha E-catenin, cadherin-associated protein or renal carcinoma antigen NY-REN-13. Catenin alpha 1 is a member of the catenin protein family, which also includes the catenin beta, catenin gamma and catenin delta proteins. Catenin alpha 1 is an important actin binding protein and has also been shown to function as a tumor suppressor (Piao et al. 2014, Silvis et al. 2014). |
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Rat Chicken Xenopus laevis - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by peptide-affinity chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide derived from the C-terminus of mouse catenin alpha 1
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
0.1 ug/ml | 1 ug/ml |
| Immunofluorescence | |
2 ug/ml | 5 ug/ml |
| Immunohistology - Paraffin 1 | |
2 ug/ml | 10 ug/ml |
| Immunoprecipitation | |
5 ug/ml | |
| Western Blotting | |
1 ug/ml |
- 1 Heat-induced epitope retrieval is required for IHC on formalin-fixed paraffin-embedded tissue
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti catenin alpha 1 antibody recognizes a band of approximately 100 kDa in HeLa cell lysate
- UniProt
- P35221
- Entrez Gene
- CTNNA1
- GO Terms
- GO:0007155 cell adhesion
- GO:0005829 cytosol
- GO:0005198 structural molecule activity
- GO:0005911 cell-cell junction
- GO:0005912 adherens junction
- GO:0008013 beta-catenin binding
- GO:0015629 actin cytoskeleton
- GO:0016342 catenin complex
- GO:0017166 vinculin binding
- View More GO Terms
- GO:0034332 adherens junction organization
- GO:0042692 muscle cell differentiation
- GO:0043297 apical junction assembly
- GO:0045295 gamma-catenin binding
- GO:0045296 cadherin binding
- GO:0051149 positive regulation of muscle cell differentiation
- GO:0071681 cellular response to indole-3-methanol
MCA6033
150504
159140
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with CATENIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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