XRN2 antibody | OTI5F4

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Mouse anti XRN2

XRN2 antibody recognizes XRN2, also known as DHP protein, 5'-3' exoribonuclease 2, or Dhm1-like protein (mouse homolog).

XRN2 Antibody with Control Lysate

XRN2 antibody recognizes XRN2, also known as DHP protein, 5'-3' exoribonuclease 2, or Dhm1-like protein (mouse homolog).

Product Type
PrecisionAb™ Monoclonal
Clone
OTI5F4
Isotype
IgG2b
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VMA00725 WB 100 µl
VMA00725KT WB 2 Westerns
With Lysate 400µg
Mouse anti Human XRN2 antibody recognizes XRN2 , also known as DHP protein, 5'-3' exoribonuclease 2 and Dhm1-like protein (mouse homolog).

XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for XRN2; however, their full-length nature is not known (provided by RefSeq, Jul 2008).

Mouse anti Human XRN2 antibody detects a band of 110 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from ascites
Preparation
20μl Mouse monoclonal antibody affinity purified on Protein G from ascites
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Immunogen
E. coli-derived recombinant protein of amino acids 677-779 of human XRN2

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Storage
Antibody: Store undiluted at -20oC, avoiding repeated freeze thaw cycles.

Lysate: Store lyophilized lysate at -20°C. After reconstitution aliquot and store at -20°C for up to 3 months or at -80°C for longer term storage.
Shelf Life
As supplied, 12 months from date of despatch
Shelf Life
As supplied, 12 months from date of despatch

More Information

UniProt
Q9H0D6 Related reagents
Entrez Gene
XRN2 Related reagents
GO Terms
GO:0005515 protein binding
GO:0000738 DNA catabolic process, exonucleolytic
GO:0016049 cell growth
GO:0003676 nucleic acid binding
GO:0004534 5'-3' exoribonuclease activity
GO:0005730 nucleolus
GO:0006353 transcription termination, DNA-dependent
GO:0006397 mRNA processing
GO:0006401 RNA catabolic process
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0045449 regulation of transcription
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of XRN2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Western Blotting
Mouse anti XRN2 detects a band of approximately 110 kDa in HepG2 cell lysates
Western Blotting
Mouse anti XRN2 detects a band of approximately 110 kDa in HepG2 cell lysates
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P 2 ml WB
Goat anti Mouse IgG (H/L):HRP STAR207P 2 ml WB